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The U.S. ambassador to Mexico resigned Saturday amid furor over a leaked diplomatic cable in which he complained about inefficiency and infighting among Mexican security forces in the campaign against drug cartels.

U.S. Secretary of State Hillary Rodham Clinton, in Paris to meet with U.S. allies on Libya, said Carlos Pascual's decision to step down was "based upon his personal desire to ensure the strong relationship between our two countries and to avert issues" raised by President Felipe Calderon.

Clinton didn't say specifically what she was referring to, but a furious Calderon has publicly criticized Pascual's cable, which was divulged by the WikiLeaks website.

Pascual's resignation -- less than two weeks since President Barack Obama met with Calderon at the White House -- appeared to be the biggest fallout yet from thousands of sensitive U.S. diplomatic cables from around the world released by WikiLeaks. It was the first such public departure by a U.S. ambassador during the Obama administration.

Mexico's government offered a polite and muted response, offering "its best wishes to Ambassador Carlos Pascual in the duties he will undertake after concluding his post in our country."

Read more: http://www.foxnews.com/politics/2011/03/19/ambassador-mexico-resigns-following-wikileaks-cable/#ixzz1HCRNTLzC